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KMID : 0387719950060010001
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Korean Journal of Blood Transfusion
1995 Volume.6 No. 1 p.1 ~ p.8
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Evaluation of 51 Cr labelled In-vivo Crossmatching Test
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임채승
임춘수/이건/김영기/이갑노
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Abstract
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For the evaluation of the 51Cr labelled in-vivo crossmatching test as a transfusion safety test, We examined the viability of the thransfused autologous and heterologous 51Cr labelled red cell at 1 hour and 24 hour in 6 normal volunteers and 4
patients
whose RBC had been stored in CPDA-1 media from 1 day to 30 day.
In both autologous transfusion control group (n=3) and allogeneic transfusion control group(n=3), the in-vivo RBC survival rate were more than 70% at 1 hour and 24 hour compared to that of basal 3 minute result(percent counted as 100%), and the
eluted
free radioisotope activity was less than 5% compared to that of whole blood, The crossmatch incompatible patient group also satisfied the safe transfusion criteria. The mean labelling efficiency which was tested in three patients was more than
95%
and
also satisfactory to reliable test.
We concluded that in-vivo crossmatching test using 51Cr radioisotope would give us valuable informations about transfusion safety, especially in serologically incompatible patients.
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